Minimally invasive endoscopy
Imaging through multimode fibre is currently the core research activity of Complex Photonics group. This methodology utilises light transport through standard multimode optical fibres to perform lensless minimally invasive micro-endoscopy. In 2012 we have demonstrated the modalities of bright- and dark-field imaging and scanning fluorescence microscopy at acquisition rates that allow observation of dynamic processes such as Brownian motion of mesoscopic particles. Furthermore, we have shown how such control can realize a new form of mode converter and generate various types of advanced light fields such as propagation-invariant beams and optical vortices. This possibilities represent a great promise for in-vivo bio-medical imaging, allowing advanced methods such as light-sheet or STED microscopy to be introduced into deep regions of unrestraint and awake animal models. Our current research efforts focuses on allowing these methods in flexible geometries, increasing the speed of acquisition and first in-vivo experiments in animal models.
T Cizmar & K Dholakia Exploiting multimode waveguides for pure fibre-based imaging. Nature Communications 3 1027 (2012)
T Cizmar & K Dholakia Shaping the light transmission through a multimode optical fibre: complex transformation analysis and applications in biophotonics. Optics Express 19(20) 18871-18884 (2011)